The Simpsons are ugly-looking, and they should be. That's what works. That's one of the things that's funny.

Seth MacFarlane’s quote speaks to the deliberate design choices behind the appearance of characters in The Simpsons, particularly their ugliness. He suggests that the unattractive nature of the characters is not a flaw, but rather an essential aspect of what makes the show work. In a way, the ugly and exaggerated design choices contribute to the humor of the show, making it stand out from other animated shows that may rely on more traditionally appealing or idealized characters. The contrast between the characters' looks and the complex, witty stories is part of the show's charm and appeal.

MacFarlane’s comment reflects his understanding of how visual comedy works. The ugliness of the characters in The Simpsons plays into the show’s broader comedic tone, where much of the humor is absurd and often satirical. By intentionally making the characters less than visually perfect, the show sets a tone that allows for more irreverence and unconventional storytelling, which is a key part of its success. It challenges the typical conventions of what animated characters are “supposed” to look like, using contrast as a source of humor.

The quote also highlights MacFarlane’s respect for The Simpsons’ innovative approach to animation. As the creator of Family Guy, MacFarlane clearly sees the value in how The Simpsons uses non-traditional animation styles to enhance the show’s overall comedic effect. This insight speaks to the freedom that comes with breaking away from conventional aesthetics to prioritize the show’s message and humor instead.

The origin of this quote likely comes from MacFarlane’s own admiration for The Simpsons, which has had a significant impact on animated television. MacFarlane, known for his own bold and unconventional animated shows, acknowledges how the unattractive characters of The Simpsons contribute to its unique comedic voice. This quote reflects how animation can break traditional norms to create something innovative and funny, and how visual choices can amplify a show’s overall impact.