Everybody in my family had a real sick, twisted sense of humor. Most of the jokes we make in our house, we would just never even dream of making anywhere else. Just sick, horrible stuff. That wasn't anything new to college.

In this quote, Seth MacFarlane reflects on the dark and twisted sense of humor that was prevalent in his family. He describes the jokes made at home as being sick and horrible, emphasizing that these types of jokes were so unconventional and edgy that they wouldn't be made in more public or formal settings. MacFarlane's comment suggests that humor in his household was both extreme and unfiltered, indicating a family culture where boundary-pushing humor was normal.

MacFarlane also highlights how this unconventional humor shaped his experience in college, noting that it wasn’t anything new for him when he encountered similar edgy humor in that setting. This suggests that the environment he grew up in influenced his comedic style and comfort level with dark or offensive humor. For MacFarlane, the line between what is acceptable and what is not seems to have been blurred by the type of humor he was exposed to early on.

The quote also illustrates how humor can serve as a cultural bond within families, even if it may not always align with societal norms. By sharing these extreme jokes, MacFarlane's family likely formed a strong internal connection, with humor serving as a means of bonding, albeit in a way that others outside the family might find disturbing. This context also sheds light on MacFarlane’s later work, which often features dark, satirical, and boundary-pushing humor, especially in shows like Family Guy.

The origin of this quote lies in MacFarlane's formative years and his family environment, which shaped his approach to comedy. His acknowledgment of the twisted humor he grew up with helps explain the edginess and satire that pervades his work today. MacFarlane’s openness about the impact of his family’s humor reveals the personal and cultural roots of his comedic style, which often tests the limits of what’s considered acceptable.