Every false religion is going to be free because it's linked to the kingdom of darkness that operates in the world. And Christians, whatever the label of religious freedom might be in its broadest sense, Christians are always the target even with religious freedom, of the hostility of sinners.

John MacArthur’s quote addresses the tension between religious freedom and the challenges faced by Christians in a world where competing religions and worldviews exist. MacArthur suggests that false religions are allowed to operate freely because they are connected to what he refers to as the "kingdom of darkness"—a symbolic representation of forces that oppose Christian beliefs. He implies that such religions align with negative or harmful ideologies, making them more accepted and protected in society.

The second part of the quote highlights a critical perspective on Christianity within the context of religious freedom. Despite the legal protections for religious freedom, MacArthur argues that Christians remain targets of hostility and persecution. This hostility, he claims, comes from those who reject the teachings of Christianity, or from what he calls the "sinners", who resist the moral and ethical demands of the Christian faith.

MacArthur’s words reflect his belief that Christianity is often marginalized or attacked, even in societies where religious freedoms are recognized. He suggests that Christians, due to their values and teachings, inevitably face opposition, particularly in cultures that increasingly embrace relativism or secularism. This resistance, in his view, is not merely a difference of opinion but a deeper spiritual conflict, with Christianity as a primary target.

Ultimately, MacArthur’s quote is a commentary on the persecution and challenges that Christians might face in a society that promotes religious freedom but also harbors animosity toward their beliefs. His message suggests that true religious freedom is not just about the ability to practice faith but also about navigating the hostility and opposition that can arise when one’s beliefs challenge the prevailing culture.