My high-school coach Tony Reginelli was kind of famous for 'Reggie-isms,' kind of like 'Yogi-isms.' He always said if you want to be a good quarterback, when sprinting left you want to be amphibious and throw left-handed. I told him, 'You mean ambidextrous, coach?'

The quote by Peyton Manning humorously recalls advice from his high-school coach, Tony Reginelli, who was known for his quirky sayings called "Reggie-isms," similar to the famous "Yogi-isms" popularized by Yogi Berra. These sayings often combined humor and wisdom, offering memorable but sometimes puzzling guidance to players.

One of Reginelli’s memorable pieces of advice was that a good quarterback sprinting left should be "amphibious" and throw left-handed. Manning’s witty response—correcting the coach with "ambidextrous"—highlights the coach’s playful misuse of words. The term “amphibious” refers to creatures that live both on land and water, while “ambidextrous” means being able to use both hands equally well, which makes more sense for a quarterback.

The origin of this quote lies in Manning’s reflection on his formative years and the colorful coaching style that influenced him. It shows how coaches often use humor and creative expressions to teach important skills, even if the wording isn’t always precise.

Overall, the quote captures the mix of respect and lightheartedness in the coach-player relationship. It also underscores how memorable sayings—whether perfectly accurate or not—can leave a lasting impression and shape an athlete’s mindset.