Everyone hooks up with George Clooney. He's a genuinely cool guy. He's using his powers for good.

In this quote, William H. Macy speaks about George Clooney and his reputation as a charismatic and genuinely cool guy. Macy humorously suggests that "everyone hooks up with George Clooney," referring to how Clooney is universally liked and admired in the industry. This could imply that Clooney has a natural ability to form strong, positive relationships with people, making him approachable and well-liked by his peers.

Macy also highlights that Clooney uses his powers for good, meaning that Clooney’s influence and success are directed towards positive causes. Clooney is known for his philanthropic work and advocacy on social and political issues, and Macy is acknowledging that Clooney leverages his fame and resources to make a difference in the world, rather than merely enjoying his celebrity status for personal gain. This adds a layer of respect to the admiration Macy expresses, suggesting that Clooney is not only a likable person but also someone who makes a meaningful impact.

By calling Clooney "cool," Macy is referring not just to his social demeanor, but also to his ability to balance fame, humanity, and success. The term "cool" in this context is used to describe someone who is not only popular but also genuine, approachable, and respected for their actions and character.

Ultimately, Macy’s quote reflects his admiration for Clooney’s ability to maintain a grounded and positive image while using his celebrity status for the greater good. It emphasizes the importance of leveraging one’s influence in a responsible way, and it highlights Clooney as a role model in both the entertainment industry and beyond.